Dynamic megaceutics is a pre-clinical research laboratory with 100 % accuracy in delivering the result datas with human end points through anatomical and pathophysiological or biomarker level of human diseases. Our test models undergo various assesments which includes phenotype, cytology, biochemistry and expression profiles.
Dynamic megaceutics is a pre-clinical research laboratory with 100 % accuracy in delivering the result datas with human end points through anatomical and pathophysiological or biomarker level of human diseases. Our test models undergo various assesments which includes phenotype, cytology, biochemistry and expression profiles.
Dynamic megaceutics is a research laboratory that focuses on the modelling of human disease on zebrafish to replicate the anatomical and pathophysiological or biomarker levels of human disease. Our models can reproduce the end points of humans in a short period of time frame with the objective of providing accurate results.
We create our own cell culture for modelling and analyze the compound activity with human end points and the compound undergoes network pharmacology studies. We precisely resolve candidate activity, through our experience of monitoring various compounds in zebrafish models that mimic human pathophysiology and anatomical level along with the help of network pharmacology.
The zebrafish which are in good condition are selected and a chemical mutagen is used to induce random point mutation and genotype screens are performed in the progeny to identify the progeny fish carrying a point mutation in gene associated with the desired disease and then the phenotypic screens are performed to further identify the model organism that meets human end points regarding the diseases.
Network Pharmacology approaches can serve as a valuable tool for evidence-based Ayurveda to understand the medicines putative actions, indications, and mechanisms. A major portion of the network pharmacology is network analysis which mainly covers attribute analysis, topological analysis, network structure and stability, flow (flux) balance analysis and network models.
A molecular dynamics simulation is a physics-based approach for understanding atom level motion and interactions of bio-molecules using Newton’s physics. Molecular dynamics simulation helps to analyze molecular interactions between bio-molecules in a dynamic environment, to be much more accurate and mimics the interactions as would happen in a cellular atmosphere.
The zebrafish which are in good condition are selected and a chemical mutagen is used to induce random point mutation and genotype screens are performed in the progeny to identify the progeny fish carrying a point mutation in gene associated with the desired disease and then the phenotypic screens are performed to further identify the model organism that meets human end points regarding the diseases.
Network Pharmacology approaches can serve as a valuable tool for evidence-based Ayurveda to understand the medicines putative actions, indications, and mechanisms. A major portion of the network pharmacology is network analysis which mainly covers attribute analysis, topological analysis, network structure and stability, flow (flux) balance analysis and network models.
A molecular dynamics simulation is a physics-based approach for understanding atom level motion and interactions of bio-molecules using Newton’s physics. Molecular dynamics simulation helps to analyze molecular interactions between bio-molecules in a dynamic environment, to be much more accurate and mimics the interactions as would happen in a cellular atmosphere.
